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ProGen2-xlarge

Training compute
1.4×10²² FLOP
Parameters
6.4B
Published
Jun 27, 2022

ProGen2-xlarge is an AI model developed by Salesforce Research, Columbia University and Johns Hopkins University (United States), first published in June 2022. It works in the biology domain, on tasks such as proteins, protein generation and protein or nucleotide language model (plm/nlm).

Training it took an estimated 1.4×10²² FLOP of compute (estimation method: hardware,third-party estimation). The model has 6,400,000,000 parameters. It was trained on roughly 350B datapoints. Training ran on Google TPU v3. The compute alone is estimated at $12K in 2023 dollars.

Access: Open weights (unrestricted). Its weights are openly available. The reference paper has 507 citations. Epoch AI rates the confidence of this record as confident.

Full record
Organization
Salesforce Research, Columbia University, Johns Hopkins University
Country of organization
United States
Domain
Biology
Task
Proteins, Protein generation, Protein or nucleotide language model (pLM/nLM)
Training compute
1.4×10²² FLOP
Compute estimation method
Hardware, Third-party estimation
Parameters
6,400,000,000
Dataset size
350B
Training hardware
Google TPU v3
Training cost (2023 USD)
$12K
Model accessibility
Open weights (unrestricted)
Open weights
Yes
Citations
507
Epoch confidence
Confident
More from Salesforce Research,Columbia University,Johns Hopkins University
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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