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MSA Transformer

Training compute
5.5×10²¹ FLOP
Parameters
100M
Published
Feb 13, 2021

MSA Transformer is an AI model developed by Facebook AI Research, University of California (UC) Berkeley and New York University (NYU) (United States and France), first published in February 2021. It works in the biology domain, on tasks such as proteins, protein or nucleotide language model (plm/nlm), protein contact and distance prediction and protein folding prediction.

Training it took an estimated 5.5×10²¹ FLOP of compute (estimation method: operation counting). The model has 100,000,000 parameters. It was trained on roughly 1.4T datapoints. Training ran on 32 NVIDIA Tesla V100 DGXS 32 GB. The compute alone is estimated at $13K in 2023 dollars.

Access: Open weights (unrestricted). Its weights are openly available. The reference paper has 644 citations. Epoch AI rates the confidence of this record as likely.

Full record
Organization
Facebook AI Research, University of California (UC) Berkeley, New York University (NYU)
Country of organization
United States, France
Domain
Biology
Task
Proteins, Protein or nucleotide language model (pLM/nLM), Protein contact and distance prediction, Protein folding prediction
Training compute
5.5×10²¹ FLOP
Compute estimation method
Operation counting
Parameters
100,000,000
Dataset size
1.4T
Training hardware
NVIDIA Tesla V100 DGXS 32 GB
Chips used
32
Training power draw
16.2 kW
Training cost (2023 USD)
$13K
Model accessibility
Open weights (unrestricted)
Open weights
Yes
Citations
644
Epoch confidence
Likely
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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