Improved motif-scaffolding with SE(3) flow matching is an AI model developed by University of Oxford, Massachusetts Institute of Technology (MIT) and Microsoft Research AI for Science (United Kingdom and United States), first published in January 2024. It works in the biology domain, on tasks such as protein design.
Training it took an estimated 1.6×10¹⁹ FLOP of compute (estimation method: hardware). The model has 16,800,000 parameters. Training ran on 2 NVIDIA RTX A6000 for about 144 hours.
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