Live
AI models

HyenaDNA

Training compute
1.8×10²¹ FLOP
Parameters
6.6M
Published
Jun 27, 2023

HyenaDNA is an AI model developed by Stanford University, Harvard University, Mila - Quebec AI (originally Montreal Institute for Learning Algorithms) and University of Montreal / Université de Montréal (United States and Canada), first published in June 2023. It works in the biology domain, on tasks such as protein or nucleotide language model (plm/nlm).

Training it took an estimated 1.8×10²¹ FLOP of compute (estimation method: hardware). The model has 6,600,000 parameters. It was trained on roughly 2.9B datapoints. Training ran on 8 NVIDIA A100 for about 672 hours. The compute alone is estimated at $5K in 2023 dollars.

Access: Open weights (restricted use). Its weights are openly available. The reference paper has 477 citations. Epoch AI rates the confidence of this record as confident.

Full record
Organization
Stanford University, Harvard University, Mila - Quebec AI (originally Montreal Institute for Learning Algorithms), University of Montreal / Université de Montréal
Country of organization
United States, Canada
Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)
Training compute
1.8×10²¹ FLOP
Compute estimation method
Hardware
Parameters
6,600,000
Dataset size
2.9B
Training hardware
NVIDIA A100
Chips used
8
Training time
672 h
Training power draw
6.4 kW
Training cost (2023 USD)
$5K
Numerical format
FP16
Model accessibility
Open weights (restricted use)
Open weights
Yes
Citations
477
Epoch confidence
Confident
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
← All ai models