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FoldFlow2

Training compute
7.6×10²¹ FLOP
Published
May 30, 2024

FoldFlow2 is an AI model developed by Dreamfold, University of Montreal / Université de Montréal, McGill University and University of Oxford (Canada and United Kingdom), first published in May 2024. It works in the biology domain, on tasks such as protein generation and protein design.

Training it took an estimated 7.6×10²¹ FLOP of compute (estimation method: hardware). It was trained on roughly 48M datapoints. Training ran on 2 NVIDIA A100 for about 96 hours.

Access: Open weights (non-commercial). Its weights are openly available. It is built on top of ESM2-650M. The reference paper has 49 citations. Epoch AI rates the confidence of this record as confident.

Full record
Organization
Dreamfold, University of Montreal / Université de Montréal, McGill University, University of Oxford
Country of organization
Canada, United Kingdom
Domain
Biology
Task
Protein generation, Protein design
Training compute
7.6×10²¹ FLOP
Compute estimation method
Hardware
Dataset size
48M
Training hardware
NVIDIA A100
Chips used
2
Training time
96 h
Training power draw
1.6 kW
Model accessibility
Open weights (non-commercial)
Open weights
Yes
Base model
ESM2-650M
Citations
49
Epoch confidence
Confident
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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