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ESM1v

Training compute
1.4×10²⁰ FLOP
Parameters
650M
Published
Nov 17, 2021

ESM1v is an AI model developed by Facebook AI Research, New York University (NYU) and University of California (UC) Berkeley (United States and France), first published in November 2021. It works in the biology domain, on tasks such as proteins, protein or nucleotide language model (plm/nlm) and protein pathogenicity prediction.

Training it took an estimated 1.4×10²⁰ FLOP of compute (estimation method: hardware). The model has 650,000,000 parameters. It was trained on roughly 22.1B datapoints. Training ran on 64 NVIDIA V100.

Access: Open weights (unrestricted). Its weights are openly available. The reference paper has 713 citations. Epoch AI rates the confidence of this record as confident.

Full record
Organization
Facebook AI Research, New York University (NYU), University of California (UC) Berkeley
Country of organization
United States, France
Domain
Biology
Task
Proteins, Protein or nucleotide language model (pLM/nLM), Protein pathogenicity prediction
Training compute
1.4×10²⁰ FLOP
Compute estimation method
Hardware
Parameters
650,000,000
Dataset size
22.1B
Training hardware
NVIDIA V100
Chips used
64
Training power draw
38.7 kW
Model accessibility
Open weights (unrestricted)
Open weights
Yes
Citations
713
Epoch confidence
Confident
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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