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ESM1-670M (UR50/S)

Training compute
4.4×10²⁰ FLOP
Parameters
669.2M
Published
Aug 31, 2020

ESM1-670M (UR50/S) is an AI model developed by Facebook AI Research and New York University (NYU) (United States and France), first published in August 2020. It works in the biology domain, on tasks such as proteins, protein or nucleotide language model (plm/nlm), mutation prediction and protein contact and distance prediction.

Training it took an estimated 4.4×10²⁰ FLOP of compute (estimation method: operation counting). The model has 669,200,000 parameters. It was trained on roughly 27.8B datapoints. Training ran on 128 NVIDIA V100. The compute alone is estimated at $967 in 2023 dollars.

Access: Open weights (unrestricted). Its weights are openly available. The reference paper has 2,637 citations. Epoch AI rates the confidence of this record as confident.

Full record
Organization
Facebook AI Research, New York University (NYU)
Country of organization
United States, France
Domain
Biology
Task
Proteins, Protein or nucleotide language model (pLM/nLM), Mutation prediction, Protein contact and distance prediction
Training compute
4.4×10²⁰ FLOP
Compute estimation method
Operation counting
Parameters
669,200,000
Dataset size
27.8B
Training hardware
NVIDIA V100
Chips used
128
Training power draw
78.2 kW
Training cost (2023 USD)
$967
Model accessibility
Open weights (unrestricted)
Open weights
Yes
Citations
2,637
Epoch confidence
Confident
More from Facebook AI Research,New York University (NYU)
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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