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Boltz-2

Published
Jun 6, 2025

Boltz-2 is an AI model developed by Massachusetts Institute of Technology (MIT), Recursion Pharmaceuticals, ETH Zurich and Valence Labs (United States, Switzerland and Canada), first published in June 2025. It works in the biology domain, on tasks such as protein interaction prediction and protein-ligand binding affinity prediction.

Epoch AI has no training-compute estimate for this model. Training ran on 188 NVIDIA A100,NVIDIA H100 NVL.

Access: Open weights (unrestricted). Its weights are openly available.

Full record
Organization
Massachusetts Institute of Technology (MIT), Recursion Pharmaceuticals, ETH Zurich, Valence Labs
Country of organization
United States, Switzerland, Canada
Domain
Biology
Task
Protein interaction prediction, Protein-ligand binding affinity prediction
Training hardware
NVIDIA A100, NVIDIA H100 NVL
Chips used
188
Model accessibility
Open weights (unrestricted)
Open weights
Yes
Citations
0
SourceEpoch AI, 'AI Models'. Published online at epoch.ai. Retrieved 2026-07-29 from https://epoch.ai/data/ai-models. Licensed under CC BY 4.0.
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